相关实验视频
Updated: Jul 1, 2025
07:55
The Influence of Liver Resection on Intrahepatic Tumor Growth
Published on: April 9, 2016
9.4K
肝移植后发作的临床影响和危险因素:一项嵌套病例对照研究
Minyu Kang1, Hwa-Hee Koh1, Deok-Gie Kim1
1Department of Surgery, The Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Republic of Korea.
概括
肝移植后的发作会影响移植的存活率. 关键的危险因素包括低BMI,较老的捐赠者年龄,手术内置换疗法和快速的变化,需要主动管理.
科学领域:
- 腎病學和肝病學.
- 神经学 神经学
- 移植医学 移植医学
背景情况:
- 发作是肝移植 (LT) 后的一个常见的神经并发症.
- 关于LT后发作的临床影响和特定风险因素的研究有限.
- 了解这些因素对于改善患者治疗结果至关重要.
研究的目的:
- 研究发作对肝移植后移植存活率的临床影响.
- 确定与LT后发作发作相关的独立风险因素.
- 分析特定临床变量与LT后发作的发生之间的关系.
主要方法:
- 采用了一个嵌套的病例控制研究设计.
- 在LT后一年内发生发作的患者与对照组1:5匹配.
- 使用多变量逻辑回归进行了生存和风险因素分析.
主要成果:
- 发作发生在4.9%的患者 (61/1243) 中,中位数为LT后11天.
- 发作组的五年移植存活率明显较低 (50.6%与78.2%,p < 0.001).
- 发作的独立风险因素包括BMI<23 kg/m2,捐赠者年龄≥45岁,手术内连续置换疗法和水平≥4 mmol/L.
结论:
- 肝移植后的发作与显著更差的移植存活率有关.
- 特定因素,如低BMI,较老的捐赠者年龄,手术内RRT和快速的变化预测了发作风险.
- 积极识别和管理这些风险因素对于防止LT后的扣押和改善移植结果至关重要.
更多相关视频
09:16Use of a Wireless Video-EEG System to Monitor Epileptiform Discharges Following Lateral Fluid-Percussion Induced Traumatic Brain Injury
Published on: June 21, 2019
25.6K
04:51Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy
Published on: April 11, 2019
9.4K
相关概念视频
01:24Arteries of the Lower Limbs
188
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
188
01:13Seizures: Classification
341
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
341