牙周病与成人阻塞性睡眠呼吸暂停之间的关系:系统性审查
Edoardo Bianchi1, Marzia Segù1, Andrea Toffoli1
1Department of Medicine and Surgery, Center of Dentistry, University of Parma, Via Gramsci 14, Parma 43126, Italy.
Dental research journal
|March 13, 2024
概括
这一综述表明,在成年人中,牙周炎和阻塞性睡眠呼吸暂停 (OSA) 之间存在联系. 虽然没有证明因果关系,但证据表明存在合理的关联,可能是由于炎症或共同的风险因素.
科学领域:
- 牙周病学 牙周病学
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
背景情况:
- 牙周炎和阻塞性睡眠呼吸暂停 (OSA) 是普遍存在的慢性疾病.
- 这两种情况都与系统性健康问题有着独立的联系.
- 了解潜在的关联对于全面的患者护理至关重要.
研究的目的:
- 系统地审查关于牙周炎和成人OSA之间关联的科学证据.
- 根据现有研究,评估关系的强度和性质.
- 识别知识上的差距,并建议未来的研究方向.
主要方法:
- 纵向,队列和病例控制研究的系统审查.
- 在MEDLINE/PubMed搜索了涉及患有牙周炎和OSA的成年人的研究.
- 使用纽卡斯尔-太华尺度进行数据提取和质量评估.
主要成果:
- 包括14项研究,所有这些研究都检查了牙周炎与OSA的关联.
- 十一项研究报告说,这两种疾病之间存在显著的积极关系.
- 三项研究没有发现统计学上显著的关联;没有研究评估因果关系.
结论:
- 有可信的证据支持牙周炎和OSA之间存在关联.
- 潜在的机制包括系统性炎症,口腔呼吸和共同的风险因素.
- 需要进一步的观察和随机对照试验来阐明相互作用机制.
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