从哪里开始呢? 爱尔兰紧急情况部抗菌药物排放 (EDAD) 研究:一个多中心,前性队列分析
Aisling Rafferty1,2, Alida Fe Talento3,4,5, Richard Drew3,6,7
1Department of Pharmacy, Children's Health Ireland at Temple Street, Dublin, Ireland.
JAC-antimicrobial resistance
|March 13, 2024
概括
在爱尔兰,9.5%的急诊室 (ED) 患者在出院后获得了抗菌素处方. 准则的遵守率为64%,突出显示了需要改善的抗菌药物管理 (AMS) 领域.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 临床药房 临床药房
背景情况:
- 抗微生物耐药性是一个日益增长的全球健康威胁.
- 在急诊室 (ED) 中优化抗微生物药物的使用对于管理至关重要.
- 需要了解爱尔兰ED的当前处方模式.
研究的目的:
- 确定从爱尔兰ED出院的患者中获得抗菌素处方的患者的百分比.
- 分析这些处方的适用情况,感染分类和指导方针遵守情况.
- 确定在ED中进行抗微生物管理 (AMS) 干预的机会.
主要方法:
- 在八家爱尔兰医院进行了多中心前性队列分析.
- 从ED出院的患者记录 (1个月以上) 被审查.
- 收集了每家医院30份抗生素处方的数据,包括指示和遵守指南.
主要成果:
- 在2619名被审查的患者中,9.5%的患者从ED获得了抗菌药物处方.
- 大多数 (63%) 是可能的细菌感染.
- 关键的适应症包括皮肤/软组织,耳鼻喉和尿道感染,总体符合指导方针的比例为64%.
结论:
- 在ED中,存在着针对抗微生物药物管理干预措施的重大机会.
- 建议包括指南审查,推迟处方,改善诊断和加强教育.
- 优化抗微生物药物处方可以打击耐药性并改善患者的治疗结果.
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