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婴儿先天性心脏手术后胆胸病的危险因素:单中心回顾性研究
Rui-Gui Zhang1,2,3, Yu-Mei Liu2,3,4, Zhi-Ye Yao2,3
1The Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510260, People's Republic of China.
Therapeutics and clinical risk management
|March 13, 2024
概括
接受先天性心脏手术的婴儿面临着胆胸病的风险. 过早分娩,长时间通风和低白蛋白是婴儿这种疾病的关键危险因素.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 新生儿手术 新生儿手术
- 胸部外科手术 胸部外科手术
背景情况:
- 胆胸病是婴儿先天性心脏病手术后的一种罕见并发症.
- 了解婴儿胆胸病的风险因素至关重要,因为它在这个年龄组的发病率更高.
研究的目的:
- 确定和分析婴儿先天性心脏手术后与胆胸相关的危险因素.
主要方法:
- 对176名接受先天性心脏手术的婴儿 (2016-2020年) 的回顾性研究.
- 根据胆胸发生情况,患者被分为对照组和病例组.
- 应用单变量和多变量逻辑回归分析来确定发病率和影响因素.
主要成果:
- 胆胸病的总发病率为2.02%,年均发病率在1.55%至3.17%之间.
- 多变量分析确定了手术后的白蛋白水平 (OR=0.095),手术前的机械呼吸 (OR=1.053) 和早产 (OR=5.783) 作为显著的危险因素.
结论:
- 过早分娩,手术前延长的机械通风和手术后低白蛋白被确定为患有先天性心脏病的婴儿肌胸病的危险因素.
- 患有胆胸部的婴儿经历了感染率的增加,更需要呼吸支,长时间的胸部排水和长时间的住院.
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