在初级保健中,中年和老年人中认知障碍和抑郁症之间的关系
Alex D Federman1, Jacqueline Becker1, Fernando Carnavali1
1Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Gerontology & geriatric medicine
|March 13, 2024
概括
抑郁症与老年人未被发现的认知障碍有关. 抑郁症的严重程度增加与认知问题的更高率相关,这表明需要在初级保健中进行综合查.
科学领域:
- 老年医学 老年医学
- 神经学 神经学
- 精神病学是一个精神病学.
背景情况:
- 认知障碍在老年人群中越来越令人担忧.
- 抑郁症在初级保健机构中很普遍,并可能影响认知功能.
- 早期发现认知障碍对于及时干预至关重要.
研究的目的:
- 在患有抑郁症的初级保健患者中调查以前未被发现的认知障碍的患病率.
- 为了检查抑郁症严重程度和认知障碍之间的关系.
- 为了为临床实践提供有关这两种疾病查的信息.
主要方法:
- 从初级保健中招募了855名55岁及以上没有先前痴呆症或轻度认知障碍史的患者队列.
- 用蒙特利尔认知评估 (MoCA) 评估认知功能.
- 用患者健康问卷-8 (PHQ-8) 评估抑郁症的严重程度.
主要成果:
- 认知障碍在22.9%的轻度抑郁,27.4%的中度抑郁,41.8%的严重抑郁患者中被检测到.
- 在多变量分析中发现严重抑郁症和认知障碍之间存在显著的关联 (p < .0001).
- 认知障碍的患病率随着抑郁症的严重程度逐渐增加.
结论:
- 在初级保健患者中,抑郁症与以前未被识别的认知障碍密切相关.
- 初级保健医生应该考虑实施或扩大对抑郁症和认知障碍的查.
- 综合查可以改善早期诊断和同时出现的疾病的管理.
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