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通过菌体显示进行类选择,以抑制莱什马尼亚 - 巨相互作用

Juliane Buzzon Meneghesso Verga1, Márcia A S Graminha1, Marcelo Jacobs-Lorena2

  • 1Department of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University (UNESP), Araraquara, Brazil.

Frontiers in microbiology
|March 13, 2024
PubMed
概括

研究人员确定了可以阻止Leishmania寄生虫感染宿主细胞的. 一个可以抑制Leishmania amazonensis和Leishmania infantum,为莱什曼尼病的治疗和预防提供了一个有前途的新途径.

关键词:
莱什曼 - 巨细胞相互作用配体-受体相互作用甲基循环的前性物质.菌体显示器是12-mer类库中的一个.有关内脏的莱什曼病.

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