腹组织病理学在诊断儿科腹腔疾病中的作用
Zahra Heidari1, Manijeh Khalili2, Hamidreza Mahmoudzadeh Sagheb1
1Department of Histology, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
概括
胃体组织学显示了儿科腹病 (CD) 的诊断潜力. 腹腔的组织学变化反映了十二指肠的发现,表明它是诊断儿童CD的更简单的活检部位.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 组织病理学 组织病理学
- 结核病的诊断 结核病的诊断
背景情况:
- 儿童的乳病 (CD) 诊断通常依赖于十二指肠活检.
- 评估替代性,不那么侵入性的活检部位对于改善诊断程序至关重要.
研究的目的:
- 评估胃肠组织学在怀疑患有乳病的儿科患者的诊断效用.
- 为了比较胃腹腔中的组织学发现与十二指肠中的发现,用于CD诊断.
主要方法:
- 对224名怀疑患有CD的儿科患者进行了回顾性分析.
- 包括每个患者的十二指肠和胃肠骨活检.
- 使用ROC曲线和AUC计算来确定诊断准确性的统计分析.
主要成果:
- 胃肠组织学显示了对乳病的显著诊断潜力 (AUC=0.90).
- 人体中特定的组织学特征 (细胞,密室和腺体大小) 显示出高的诊断准确性 (AUC=0.89).
- 胃的组织学变化与儿科CD患者十二指肠中观察到的变化一致.
结论:
- 胃腹膜活检是一种可行的,可能更容易的替代方案,用于诊断儿童的腹腔疾病.
- 这项研究建议在未来与更大的队列进行研究时,利用胃肠组织学标准进行研究.
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