相关实验视频
Updated: Jul 15, 2026

08:04
Murine Fetal Echocardiography
Published on: February 15, 2013
17.3K
B流/时空图像相关性 M模式超声波提供了一种新的方法来量化正常人类怀孕期间螺旋动脉重塑的数量
概括
超声波以数字方式量化螺旋动脉延伸能力,这是怀孕适应的关键标志物. 这种非侵入性方法在正常怀孕期间跟踪子宫螺旋动脉的生理重塑.
科学领域:
- 生殖医学和孕产妇和胎儿健康
- 医疗成像和超声波研究
- 血管生物学和重塑血管
背景情况:
- 在人类怀孕期间,子宫螺旋动脉经历了由胎盘外螺旋性热囊细胞的显著重塑.
- 这种重塑将低合规性动脉转化为高容量,低阻力血管,对于胎盘输液至关重要.
- 对这种血管适应的准确体内评估对于理解正常怀孕和识别潜在并发症至关重要.
研究的目的:
- 为了确定B流/时空图像相关性 (STIC) M模式超声波是否可以数字量化螺旋动脉光延伸性.
- 评估螺旋动脉延展性,作为正常人类怀孕晚期血管改造的生理指数.
- 为了将螺旋动脉张张能力的变化与胎盘生长因子 (PlGF) 和可溶性 fms-like 铁酶-1 (sFlt-1) 的母体血清水平相关联.
主要方法:
- 一项前性,纵向性,观察性研究,涉及290名怀孕正常的妇女.
- 用B流/STIC M模式超声波测量螺旋动脉延伸能力 (心缩减腹缩直径) 在三个月内.
- 在怀孕期间,在一小部分参与者中测量了母亲血清Plgf和sFlt-1水平.
主要成果:
- 螺旋动脉延伸能力从第一个 (0.17厘米) 到第二个 (0.23厘米) 和第三个 (0.26厘米) 三季度逐渐增加 (P < 0.0001).
- 螺旋动脉体积流量在三个月内显著逐步增加 (P < 0.001).
- 随着怀孕的进展,plgf/sflt-1比率显著增加,与增强的螺旋动脉延展性相关 (p < 0.001).
结论:
- B-流/STIC M模式超声波是一种有效的体内成像技术,用于数字化量化螺旋动脉延伸能力.
- 这种方法以数字方式捕捉了螺旋动脉的结构和生理扩张,因为它们在怀孕期间成为合规的血管.
- 这些发现验证了超声波作为监测正常怀孕期间子宫螺旋动脉适应性重塑的工具.
相关概念视频
Magnetic Resonance Imaging
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Ultrasonography
Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called a...
During an ultrasonography procedure, a handheld device called a...
Imaging Studies for Cardiovascular System IV: CMRI
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
Imaging Studies II: Ultrasonography
IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
Imaging Studies VII: Vascular Imaging
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...

