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Updated: Jul 1, 2025

Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
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Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy

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瘤微环境可激活纳米系统能够克服多个治疗障碍,以增强免疫/金属离子疗法

Qian Cheng1,2,3, Xiaolei Shi1,2,3, Yuzhe Chen1,2,3

  • 1Research Center for Tissue Engineering and Regenerative Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

ACS nano
|March 13, 2024
PubMed
概括

这项研究开发了一个智能纳米系统,可以在瘤微环境 (TME) 中缩小,透到深层瘤中. 它逆转了支持瘤的TME,增强了纳米药物的有效性,并使组合疗法能够改善抗瘤效果.

关键词:
不正常的瘤微环境抗瘤纳米药物 纳米药物巨细胞是什么?巨细胞是什么?通过透的透.支持瘤的微环境

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Studying the Effects of Tumor-Secreted Paracrine Ligands on Macrophage Activation using Co-Culture with Permeable Membrane Supports07:44

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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