营养不良作为挪威住院患者2年死亡率的预后因素:一项匹配的队列研究
Marte A Trollebø1, Randi J Tangvik1, Eli Skeie2
1Centre for Nutrition and Mohn Nutrition Research Laboratory, Department of Clinical Medicine, University of Bergen, Bergen, Norway.
JPEN. Journal of parenteral and enteral nutrition
|March 13, 2024
概括
住院患者的严重营养不良显著增加了两年内死亡的风险. 即使考虑到年龄,性别和并发症,这种关联仍然很强,这强调了营养不良严重程度对死亡率的重大影响.
科学领域:
- 临床营养学 临床营养学
- 老年病的医生 老年病的医生
- 流行病学 流行病学
背景情况:
- 营养不良和营养不良的风险与较高的死亡率有关.
- 营养不良严重程度对全因死亡率的影响需要进一步调查.
研究的目的:
- 用全球营养不良领导倡议 (GLIM) 标准评估营养不良风险或诊断之间的关联,以及所有原因的死亡率.
- 确定营养不良的严重程度是否与住院患者的死亡率有关.
主要方法:
- 在挪威伯根,对326名住院患者 (不包括特定群体) 进行了一项匹配的队列研究.
- 使用营养风险查2002进行营养查,并使用GLIM标准进行评估.
- 使用挪威死亡登记册追踪所有原因死亡率2年; 风险因素的考克斯回归分析.
主要成果:
- 在2年内观察到17%的死亡率 (55例死亡).
- 营养不良,而不是营养不良的风险,独立地与所有原因死亡率的增加有关 (HR 2.50).
- 在调整后,严重营养不良与死亡率 (HR 2.73) 有显著关联.
结论:
- 根据GLIM标准定义的严重营养不良与住院患者全因死亡率的增加密切相关.
- 这项研究强调了严重营养不良在这一群体的预后意义.
- 调查结果强调了在医院环境中早期识别和管理严重营养不良的需要.
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