后代的呼吸系统疾病被错误地归类为生长受限制的后代
Omri Zamstein1, Tamar Wainstock2, Eyal Sheiner1
1Obstetrics and Gynecology Division, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Pediatric pulmonology
|March 13, 2024
概括
错误地将胎儿归类为怀孕年龄 (FGR) 较小的胎儿,会增加他们患喘等儿童呼吸系统问题的风险. 这强调了需要准确的产前诊断,以避免不必要的干预,并保护长期的婴儿健康.
科学领域:
- 产周医学 产周医学
- 儿童呼吸系统健康问题
- 产科的诊断准确性 在产科的诊断准确性.
背景情况:
- 基于超声波的胎儿生长限制 (FGR) 诊断可以错误地分类适当生长的胎儿 (AGA).
- 错误的分类可能会导致不必要的干预,如早期产业诱导.
- 这些错误分类的婴儿的长期健康结果,特别是呼吸系统健康,尚不清楚.
研究的目的:
- 为了评估被错误归类为FGR.的后代的长期呼吸健康状况.
- 为了比较AGA新生儿的呼吸道发病率,有和没有错误的FGR诊断.
主要方法:
- 在第三级医院对AGA单身 (1991-2021) 的基于人口的队列分析.
- 错误分类的FGR和非FGR AGA新生儿之间的呼吸道发病率的比较.
- 卡普兰-梅尔生存分析和分层的考克斯比例风险模型用于发病率和混杂物控制.
主要成果:
- 1.0% (3249/324,620) 的AGA新生儿被错误地归类为FGR.
- 错误分类的FGR婴儿的分娩时间较早 (36.7 vs. 39.1周),儿童呼吸道发病率高于25% (33.2% vs. 26.5%).
- 观察到喘和阻塞性睡眠呼吸暂停的风险增加,独立于早产和其他因素 (aHR=1.14).
结论:
- 适当成长的新生儿被错误分类为FGR面临着显著增加的长期呼吸道发病风险.
- 这包括儿童和青少年时期喘和阻塞性睡眠呼吸暂停的发病率较高.
- 准确的产前诊断对于防止不必要的干预和减轻不良呼吸道结果至关重要.
相关概念视频
Breathing
59.2K
The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
59.2K
Acute Respiratory Failure-II
222
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
222
Pulmonary Cycle: Exhalation
1.6K
In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
1.6K
Other Pulmonary Disorders
838
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
838
Respiratory Assessment: Purpose and Indications
1.1K
Respiratory assessment is a cornerstone of nursing assessments, crucial for the early detection of patient deterioration. This evaluation transcends routine procedures, representing a critical skill nurses must master to ensure optimal patient care.
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
Objectives and Importance:
The primary goal of respiratory assessment is to evaluate patients at early risk of clinical deterioration. Since respiratory distress often precedes other signs of declining health, breathing patterns and sounds become a...
1.1K
Acute Respiratory Failure-I
206
Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
206


