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Updated: Jul 1, 2025

Author Spotlight: Simple Establishment of a Vascularized Osteogenic Bone Marrow Niche Using Pre-Cast Poly(Ethylene Glycol) (PEG) Hydrogels in an Imaging Microplate
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Author Spotlight: Simple Establishment of a Vascularized Osteogenic Bone Marrow Niche Using Pre-Cast Poly(Ethylene Glycol) (PEG) Hydrogels in an Imaging Microplate

Published on: May 19, 2023

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斯芬哥辛-1-酸盐通过刺激骨质母细胞生长和新血管化以血管内皮生长因子依赖的方式促进骨质生成

Annalena Wille1, Sarah Weske1, Karin von Wnuck Lipinski1

  • 1Institute of Molecular Medicine III, Heinrich Heine University Düsseldorf, 40225 Düsseldorf, Germany.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
|March 13, 2024
PubMed
概括

在骨质母细胞中传递的sphingosine-1-phosphate (S1P) 信号刺激血管内皮生长因子a (VEGFa),促进骨生长和血管化. 这种S1P/S1PR3通路对于骨再生和恒温至关重要.

关键词:
骨骨 μCT 的分析/量化.动物模型遗传动物模型骨建模和重塑分子通路重塑骨骨质细胞的细胞.系统生物学 骨相互作用器骨内皮细胞相互作用

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