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Updated: Jul 1, 2025

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染色体重塑因子Arid1a与Jun/Fos合作,通过表观遗传上调Siglec15表达来促进骨质细胞形成

Yongxing Zhang1,2,3,4, Hangxiang Sun1,2,3,4, Fei Huang5

  • 1Department of Orthopedics, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, PR China.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
|March 13, 2024
PubMed
概括

巨细胞中Arid1a的损失通过抑制骨质细胞分化来增加骨质量. 这种表观遗传重编程为骨质疏松症等骨质损失疾病提供了潜在的治疗策略.

关键词:
这是一个干旱的地区.在Siglec1515中使用.染色体重塑 染色体重塑的方法骨质细胞分化的分化.骨质疏松症是一种骨质疏松症.

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