针对COVID-19的免疫接种和住院患者的死亡率:一个回顾性队列
Alexandre Medeiros de Figueiredo1,2, Adriano Massuda3, Michelle Fernandez4
1Universidade Federal da Paraíba. Centro de Ciências Médicas. Departamento de Promoção da Saúde. João Pessoa, PB, Brasil.
Revista de saude publica
|March 13, 2024
概括
COVID-19疫苗显著降低了住院患者的死亡风险. 实现更高的疫苗接种覆盖率,特别是在2021年初,可以防止大量的病毒死亡.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 疫苗学 疫苗学 疫苗学
背景情况:
- 由SARS-CoV-2或COVID-19引起的严重急性呼吸系统综合征 (SARS) 导致了显著的死亡率.
- 疫苗开发旨在缓解严重疾病和死亡.
研究的目的:
- 评估COVID-19疫苗在降低SARS-CoV-2患者住院患者死亡率方面的有效性.
- 为了确定与住院COVID-19患者的死亡率相关的风险因素.
主要方法:
- 追溯队列研究分析了2021年2月至11月在巴西帕拉伊巴的数据.
- 研究了两剂疫苗接种计划,并发病症和人口因素对死亡率的影响.
- 采用描述性分析和逻辑回归 (双变量和多变量).
主要成果:
- 完整的疫苗接种计划与41.7%的死亡可能性降低有关 (OR = 0.583).
- 死亡风险因素包括任何并发症的存在 (OR = 1.627) 和80岁以上的年龄 (OR = 7.426).
- 妇女和接受私人医院治疗的患者的死亡风险降低.
结论:
- COVID-19 免疫接种有效降低死亡风险.
- 在2021年初增加疫苗接种覆盖率,可能会防止成千上万的死亡.
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