叙利亚战争期间的肺癌诊断和结果,2011-2018年
Ibrahem Hanafi1, Dana Abo Samra2, Rama Alsaqqa3
1Division of Neurology, Department of Internal Medicine, Faculty of Medicine, Damascus University, Damascus, Syria.
JAMA network open
|March 13, 2024
概括
叙利亚战争严重影响了肺癌的治疗,导致诊断延迟,生存率大幅降低,特别是在受冲突影响的地区. 由于战争导致医疗保健无法获得,患者的治疗结果明显恶化.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 战争研究 战争研究
背景情况:
- 长期的战争不成比例地影响着资源较低的国家,挑战了癌症护理系统.
- 肺癌是最致命的瘤疾病,在长期冲突期间受到显著影响.
研究的目的:
- 描述叙利亚战争期间肺癌患者的临床表现和生存结果.
- 评估冲突强度和医疗保健可及性对肺癌患者生存率的影响.
主要方法:
- 一项对5160名在2011-2018年期间在叙利亚被诊断出肺癌患者的队列研究.
- 组织学亚型的调查,TNM分类,分期,以及每年长达5年的随访.
- 与地理区域和战争强度相关的生存率和概率的分析.
主要成果:
- 在战争初期,新诊断的肺癌病例急剧下降,60-80%的人患有转移.
- 一年和五年生存率分别为13.1%和0.1%,非常低.
- 来自冲突严重地区的患者的生存率较低,与战争相关的医疗保健难以获得解释了比年龄和阶段相结合的生存率更大的变化.
结论:
- 叙利亚战争导致肺癌管理的显著下降,其特点是有限的护理和延迟诊断.
- 幸存率大幅下降,与武装冲突的强度相关.
- 迫切需要采取战略,改善冲突地区肺癌患者的医疗保健可及性和质量.
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