儿科皮肤粘膜菌症
Mariana Claudia Matei1, Sandra Castejon Ramirez, Sara Sanz Sanz
1Department of Dermatology, Hospital Miguel Servet, Zaragoza, Spain. marimatei.96@gmail.com.
Dermatology online journal
|March 13, 2024
概括
一个儿科病例的粘膜菌,一种罕见的真菌感染,发生在一个男孩急性髓母细胞白血病. 早期诊断和手术脱bridement与安福特 B的联合治疗改善了结果.
科学领域:
- 菌类学 菌类学是指菌类学.
- 儿科瘤学 儿科瘤学
- 传染性疾病 传染性疾病
背景情况:
- 粘菌菌是一种罕见的机会性真菌感染.
- 它主要影响免疫受损的个体,特别是那些患有血液病的人.
- 儿科病例很少发生,但与显著的发病率有关.
研究的目的:
- 报告一个患有急性髓母细胞白血病的儿科患者罕见的传播性皮肤粘膜瘤病例.
- 要强调诊断的挑战和成功的管理策略,对于这个机会性感染的免疫力低下的孩子.
主要方法:
- 一个9岁的男孩患有急性髓母细胞白血病和发烧性中性质疏松症,出现了紫色皮肤病变.
- 组织病理学检查显示皮肤发作与特征性真菌菌,和文化隔离Rhizopus oryzae.
- 治疗包括手术除,静脉注射安福特瑞辛B,随后是口服波萨可纳.
主要成果:
- 患者患有多个死性皮肤病变,表明皮肤梗塞.
- 通过活检证实了诊断,显示了特征性真菌元素和Rhizopus oryzae的阳性培养.
- 结合手术和抗真菌疗法导致了临床改善和成功的出院.
结论:
- 皮肤粘膜瘤,虽然很少见,但在发烧性中性衰竭的儿科患者患有血液性恶性瘤时,这是一个关键考虑因素.
- 通过活检和组织学及时诊断,加上包括手术除菌和全身抗真菌药物在内的积极治疗,对于有利的结果至关重要.
- 这一案例强调了多学科方法在治疗免疫功能低下儿童的侵入性真菌感染方面的重要性.
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