莱特勒-西韦病呈现出胃肠道和皮肤表现
Antonina Sergeevna Stadnikova1, Walaa Fadhil Abbas, Olga Borisovna Tamrazova
1Federal State Autonomous Educational Institution of Higher Education "Peoples' Friendship University of Russia" of the Ministry of Education and Science of the Russian Federation, Children's City Clinical Hospital named after PER, Bashlyaeva, Moscow Department of Health, Moscow, Russia.
Dermatology online journal
|March 13, 2024
概括
莱特勒-西韦病是一种严重的囊细胞瘤,可在婴儿中出现早期的胃肠道症状. 这一案例凸显了在婴儿诊断中考虑罕见疾病的重要性.
科学领域:
- 儿科病理学 儿科病理学
- 免疫学 免疫学 免疫学
- 皮肤病学 皮肤病学
背景情况:
- 囊细胞病包括各种多发性疾病,其特征是树突细胞,巨细胞和单细胞透.
- 这些疾病会影响各种器官,包括皮肤,症状严重程度从轻微到危及生命.
- 朗格汉斯细胞囊细胞症 (LCH) 在儿童和成人中都存在,需要多方面的诊断方法.
研究的目的:
- 审查关于囊细胞病的文献,特别关注Letterer-Siwe病.
- 介绍一个婴儿患有Letterer-Siwe疾病的案例研究.
- 强调这种罕见疾病的诊断挑战和早期临床表现.
主要方法:
- 关于囊细胞和莱特勒-西韦病的文献综述.
- 一个9个月大的女婴的临床病例介绍.
- 诊断工作包括临床,组织学和放射学评估 (隐含).
主要成果:
- 莱特勒-西威病是一种严重的,多系统的LCH形式,通常影响婴儿.
- 该案例研究详细介绍了一个婴儿,最初的表现是反复出现的胃肠道问题.
- 诊断Letterer-Siwe疾病需要临床,组织学和放射学发现的结合.
结论:
- 在婴儿中,早期识别胃肠道症状作为Letterer-Siwe疾病的潜在迹象至关重要.
- 虽然某些类型的囊细胞瘤是可以治疗的,但Letterer-Siwe病带来了重大风险.
- 这一案例强调了对儿科患者怀疑囊细胞瘤的综合诊断策略的重要性.
相关概念视频
01:30Inflammatory Bowel Disease II: Crohn's Disease
240
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
240
01:17Chronic Bowel Disorders: Introduction
450
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
450
01:27Inflammatory Bowel Disease I: Ulcerative Colitis
181
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
181
01:30Other Disorders of Digestive System
829
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
829
01:23Skin Diseases and Disorders
3.8K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.8K
01:17Gastritis-II: Pathophysiology
324
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
324