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Updated: Jul 1, 2025

Building Up a High-throughput Screening Platform to Assess the Heterogeneity of HER2 Gene Amplification in Breast Cancers
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低HER2的乳腺癌:解释免疫组织化学的挑战

Noel Chia1, Mihir Ananta Gudi2, Emad Rakha3

  • 1Department of Pathology, National University Hospital, Singapore.

Singapore medical journal
|March 13, 2024
PubMed
概括

新的研究定义了低HER2乳腺癌,确定了受益于trastuzumab-deruxtecan的患者. 目前用于人类表皮生长因子受体2 (HER2) 低状态的评分方法显示出可变性,需要进一步改进以准确地针对患者.

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Validated Immunochemical Assay for Comprehensive Determination of the Human Epidermal Growth Factor Receptor 2 Released from and Bound to Cells

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Protocol for HER2 FISH Using a Non-cross-linking, Formalin-free Tissue Fixative to Combine Advantages of Cryo-preservation and Formalin Fixation10:21

Protocol for HER2 FISH Using a Non-cross-linking, Formalin-free Tissue Fixative to Combine Advantages of Cryo-preservation and Formalin Fixation

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相关概念视频

Immunocytochemistry and Immunohistochemistry01:22

Immunocytochemistry and Immunohistochemistry

Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
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