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Updated: Jul 1, 2025

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness
08:52

Software-Assisted Quantitative Measurement of Osteoarthritic Subchondral Bone Thickness

Published on: March 18, 2022

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铁过载通过mTORC1-p70S6K/4E-BP1通路促进与血色素变异相关的关节炎

Zhiyuan Fang1, Chengwei Wang1, Jiang Zhu2

  • 1Department of Orthopaedic Surgery, The Third Affiliated Hospital of Xinjiang Medical University, Xinjiang Medical University, Urumqi 830000, China.

International immunopharmacology
|March 13, 2024
PubMed
概括

在血液染色病中,关节的铁过载促进了M1巨细胞的两极分化,恶化了骨关节炎. 这项研究表明,铁过载会通过激活突巨细胞中的mTORC1-p70S6K/4E-BP1通路而加剧软骨损伤.

关键词:
造成软骨损伤的情况.血液染色症相关的关节病变.铁过载是因为铁过载.巨细胞是一个巨细胞.机理机制 机理机制

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A RANKL-based Osteoclast Culture Assay of Mouse Bone Marrow to Investigate the Role of mTORC1 in Osteoclast Formation09:37

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Published on: March 15, 2018

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