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参与者在甲基胺戒断治疗试点研究中的经验:对保留的影响

Liam S Acheson¹, Simon Clay², Rebecca McKetin²

¹The National Drug and Alcohol Research Centre (NDARC), University of New South Wales, 22-32 King St, Randwick, NSW 2031, Australia; Alcohol and Drug Service, St Vincent's Hospital Sydney, 390 Victoria St Darlinghurst, NSW 2010, Australia; The National Centre for Clinical Research on Emerging Drugs (NCCRED), c/o University of New South Wales, 22-32 King St, Randwick, NSW 2031, Australia.

The International journal on drug policy

|March 13, 2024

概括

在临床试验中了解患者的经验对于甲基胺戒断至关重要. 积极的经验,包括信任和清晰的沟通,帮助参与者留在研究中.

科学领域:

临床心理学临床心理学
药理学药理学是指药理学的学科.
成药物药物药物药物

背景情况:

对于参与临床试验的甲基胺使用者,特别是对于非戒断干预的干预,对他们的观点的理解有限.
对这些经验的洞察力可以为更以患者为中心的临床试验设计提供信息.
这项研究侧重于使用lisdexamfetamine治疗急性甲基胺戒断的临床试验参与者的经验.

研究的目的:

探索那些完成了急性甲基胺戒断临床试验的人的实践经验.
确定影响参与者参与和留在药物使用障碍临床试验中的因素.
为未来临床试验的设计提供信息,以增强参与者的经验和坚持.

主要方法:

在对八名参与者的半结构面试中,采用了主题分析.
采访对象是完成了一项临床临床临床临床试验的病人lisdexamfetamine急性甲胺戒断.
数据收集发生在悉尼市中心一家医院的住院第三天和第六天之间.

主要成果:

参与者报告说,研究程序,试验环境和研究产品显著影响了他们的体验.
影响持续参与的关键因素包括透明和低负担的试验程序,欢迎的环境和信任的关系.
有效的沟通被认为是保持参与者的关键.

结论:

临床试验中的参与者经验以四个元主题为特征:代理,关怀-信任,安全和沟通.
参与者将这些主题与他们继续参与研究的能力直接联系在一起.
将参与者的观点纳入临床试验设计可以改善未来的参与者体验并提高研究保留率.

关键词:

临床试验临床试验是指临床试验的临床试验.甲基胺是一种甲基胺.参与者体验了参与者的经验.质量上的质量.专题分析专题分析

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