P2X7R自由的代价是神经炎症

Mingqian Fang1, Ren Lai1

  • 1Engineering Laboratory of Peptides of Chinese Academy of Sciences, Key Laboratory of Bioactive Peptides of Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, National Resource Center for Non-Human Primates, National Research Facility for Phenotypic & Genetic Analysis of Model Animals (Primate Facility), and Sino-African Joint Research Center, New Cornerstone Science Laboratory, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223, China.

Immunity
|March 13, 2024
PubMed
概括

微质,大脑的免疫细胞,通过运输/的ATPase亚单元α (NKAα1) 和P2X7受体 (P2X7R) 复合体保持静止状态. 压力会破坏这种状态,激活小质细胞,并可能导致焦虑行为.