身体活动和慢性阻塞性肺病风险:台湾的一项纵向随访研究
Yu-Hsuan Lee1, Ya-Ping Huang2, Shin-Liang Pan3
1Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan.
The American journal of the medical sciences
|March 13, 2024
概括
定期进行体力活动 (PA) 与患慢性阻塞性肺病 (COPD) 的风险明显降低. 这项研究强调了PA作为预防COPD的潜在策略.
科学领域:
- 肺部医学 肺部医学
- 预防性心脏病学 预防性心脏病学
- 公共卫生 公共卫生
背景情况:
- 慢性阻塞性肺病 (COPD) 构成了全球重大健康负担.
- 确定可修改的COPD风险因素对于有效的预防策略至关重要.
研究的目的:
- 检查身体活动 (PA) 水平与随后发展COPD的风险之间的关联.
- 为了确定更高的PA水平是否与COPD发病率降低相关.
主要方法:
- 一项基于人口的纵向随访研究,涉及台湾的59,457名参与者.
- 根据基线身体活动,参与者被分为没有正常的PA (NPA),低PA (LPA,<90分钟/周) 和高PA (HPA,≥90分钟/周) 组.
- 考克斯的比例危险回归分析被用来评估PA对COPD风险的影响在2015年后续期间.
主要成果:
- 与NPA组相比,LPA和HPA组中的个体患上COPD的风险比NPA组低20%以上.
- 对于LPA组,COPD的调整后危险比为0.72 (95% CI,0.61-0.85) 和HPA组为0.79 (95% CI,0.69-0.90).
- 低水平和高水平的体育活动都显示出对COPD发病率的统计学上显著的保护作用.
结论:
- 身体活动水平和患上COPD的风险之间存在明显的反向关系.
- 身体活动可以作为一种有价值的工具,用于预防慢性阻塞性肺病的初级预防.
- 促进定期体育活动可能是减少COPD患病率的关键公共卫生干预措施.
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