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试点研究:一个简单的基于CAD的工具,可以在乳房MRI上检测乳腺癌

Barbara I Bennani-Baiti¹, Michael Weber², Maria Bernathova²

¹Karl Landsteiner University of Health Sciences, Dr. Karl-Dorrek-Straße 30, Krems 3500, Austria; Department of Radiology, University Hospital Krems, Mitterweg 10, Krems 3500, Austria; Division of General and Pediatric Radiology, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Währinger Gürtel 18-20, Vienna 1090, Austria.

Magnetic resonance imaging

|March 13, 2024

概括

在MRI中定量评估增强乳腺组织可能表明乳腺癌. 这项试点研究发现,在评估中使用的两种对比剂之间,诊断效率没有显著差异.

科学领域:

放射学放射学是一门学科.
在瘤学瘤学.
医疗成像医学成像

背景情况:

乳腺癌的诊断依赖于像MRI这样的成像技术.
对增强乳腺组织的定量评估可能会提高诊断准确度.
了解不同对比剂的影响对于MRI疗效至关重要.

研究的目的:

评估是否定量评估增强乳腺组织的百分比表明乳腺癌在MRI.
为了确定对比剂的类型是否会影响乳房MRI的诊断效果.

主要方法:

对39名接受两次乳腺核磁共振检查的患者进行了回顾性分析,这些患者使用了不同的对比剂 (gadobenate和gadoterate).
两名盲人读者使用计算机辅助软件评估未增强和早期对比后图像.
诊断性能是通过比较增强的声素体积百分比与组织病理学结果来确定的.

主要成果:

曲线下的面积 (AUC) 值为ipsilateral增强的voxel体积范围从0.687到0.778.
考虑到背景增强,AUC得到了改善,从0.662到0.843.
在读取器或对比剂之间没有发现统计学上显著的差异 (p > 0.05).

结论:

一个CAD算法量化评估增强乳腺组织百分比可以表明乳腺癌的存在.
这项研究表明,对增强乳腺组织的定量评估是乳腺癌的可行指标.
进一步的研究可能会探索优化对比剂选择以提高诊断准确性.

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相关概念视频

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...