阿根廷的菌菌病的流行病学,一个最新的更新
Mariana Noelia Viale1, María Cecilia López-Joffre1, Andrea Nora Motter2
1Departamento Micología, Laboratorio Nacional de Referencia en Micología Clínica, Instituto Nacional de Enfermedades Infecciosas, ANLIS "Dr. Carlos G. Malbrán", Argentina.
Medical mycology
|March 13, 2024
概括
阿根廷的Coccidioidomycosis病例显著增加,大多数病例发生在男性和慢性形式中,表明诊断延迟. 提高公众意识和医疗保健培训对于更好地管理菌菌病至关重要.
科学领域:
- 临床真菌学 临床真菌学
- 传染病 流行病学 流行病学
背景情况:
- 型菌是美洲部分地区特有的真菌感染.
- 准确的疾病负担评估对于公共卫生干预至关重要.
研究的目的:
- 为了确定阿根廷的人类菌菌病的负担.
- 分析趋势并确定疾病的人口和地理模式.
主要方法:
- 在2010年至2022年间诊断的100例人类菌菌病例的回顾性审查.
- 利用双重免疫扩散测试,组织病理学,直接显微镜和Ag2/PRA基因测序进行鉴定.
主要成果:
- 记录了100例病例,主要是男性 (1.9:1比),平均年龄为41岁.
- 从2000-2009年到2010-2019年的病例显著增加 (36.51%).
- 卡塔马卡省的发病率最高;36个分离物被确定为Coccidioides posadasii. 超过一半的病例是慢性肺病或传播形式.
结论:
- 延迟诊断是由慢性和扩散性菌菌菌病的高比例表明的.
- 针对医疗保健人员的有针对性的培训和公众宣传活动是必不可少的.
- 更好地了解菌菌病的负担将有助于卫生控制措施.
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