使用问卷评估的肉症可以预测肺结核老年患者的住院死亡率
Masayoshi Kakiuchi1, Tatsuro Inoue2, Hikaru Kobayashi1
1Department of Rehabilitation, Kobe City Nishi-Kobe Medical Center, 5-7-1, Kojidai, Nishi-ku, Kobe-shi, Hyogo-ken, 651-2273, Japan.
Clinical nutrition ESPEN
|March 13, 2024
概括
通过SARC-F问卷识别的高风险显著增加了肺结核老年患者的住院死亡率. 关键指标包括难以行走和从椅子上站起来.
科学领域:
- 老年医学 老年医学
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 肺结核 (TB) 是一种严重的传染病,死亡率高.
- 随着年龄增长而导致肌肉质量和功能丧失的萨尔科佩尼亚,越来越多地被认为是各种健康结果的一个因素.
- 肺结核患者老年人肉类症和住院死亡率之间的关联仍未得到充分研究.
研究的目的:
- 为了确定使用SARC-F问卷评估的高风险是否与诊断为肺结核的老年患者的住院死亡率增加有关.
- 确定特定的SARC-F成分,这些成分有助于该患者群体的死亡风险.
主要方法:
- 一项回顾性观察性研究包括147名65岁或以上的患者,他们在2021年4月至2022年11月期间接受了活性肺结核治疗.
- 使用SARC-F问卷评估了肉症风险,得分为4或更高,表明高风险.
- 从医疗记录中提取了有关人口统计,并发症,临床参数和结果 (包括住院死亡率) 的数据.
主要成果:
- 超过63%的患者 (93/147) 呈现出高风险的肉类.
- 患有高风险肉症的患者年龄较大,BMI较低,格拉斯哥预后得分更高,小腿周长缩小.
- 卡普兰-梅尔分析显示,高风险肉类症患者的存活率显著降低 (日志等级测试,P=0.001). 后勤回归显示高风险 (OR:6.425) 和特定的SARC-F项目 (步行辅助OR:3.931;从椅子上起身OR:2.458) 是医院死亡率的重要预测因素.
结论:
- 在入院时通过SARC-F问卷识别的高风险是肺结核老年患者住院死亡的重要风险因素.
- 步行辅助和从椅子上起床困难是SARC-F的关键组成部分,与此脆弱群体的死亡率增加有关.
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