在原发性副甲状腺功能障碍患者中,对无症状甲的查是有必要的
Taryn Zabolotniuk1, Michael Guo1, Michelle Kwon1
1Department of Surgery, St. Paul's Hospital & University of British Columbia, 1081 Burrard Street, Vancouver, British Columbia, V6Z 1Y6, Canada.
American journal of surgery
|March 13, 2024
概括
初级甲状腺功能障碍症 (PHPT) 患者经常出现结石,许多患者需要泌尿器科的干预. 查结石对于有效的PHPT管理至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 腎臟病學 (nephrology) 是一種醫學專業.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 原发性偏甲状腺症 (PHPT) 与各种并发症有关.
- 结石是PHPT已知的并发症,但其患病率和管理需要进一步调查.
研究的目的:
- 研究PHPT患者中结石病的患病率,特征和治疗方法.
- 为了确定石块形成的危险因素和PHPT患者需要泌尿外科干预的需要.
主要方法:
- 对413名经过副甲状腺切除术的PHPT患者的医疗记录进行回顾.
- 分析人口统计数据,实验室结果,成像和泌尿器科咨询.
- 描述性统计和物流回归被用于数据分析.
主要成果:
- 41.9%的PHPT患者患有结石,48.6%需要泌尿外科干预.
- 石头形成的独立风险因素包括男性性别,血清电离 (iCa) 的升高,24小时尿路的升高.
- 男性性别,年龄较小,血清中25-氧维生素D (25(OH) D含量较低与需要干预的可能性更高有关.
结论:
- 在PHPT患者中存在无症状结的显著患病率.
- 在这些患者中,很大一部分需要泌尿器科的干预.
- 查和治疗结石应纳入PHPT患者管理.
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