揭示了联系:最低下静脉孔径和血栓形成风险的关系
Maofeng Gong1, Cheng Qian1, Rui Jiang1
1Department of Interventional and Vascular Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, PR China.
Academic radiology
|March 13, 2024
概括
在患有下肢深静脉血栓症 (LEDVT) 的患者中,较低的最低下腔静脉 (IVC) 直径放大百分比,特别是低于37.3%,与IVC过器 (IVCF) 放置后IVC血栓在位 (iIVCT) 风险降低有关. 这一发现表明它充当了一种保护因素.
科学领域:
- 血管外科 血管外科
- 干预性放射学 干预性放射学
- 心血管成像 - 心血管成像
背景情况:
- 下腔静脉过器 (IVCF) 用于预防下肢深静脉血栓症 (LEDVT) 患者的肺栓塞.
- 位置内IVC血栓形成 (iIVCT) 是IVCF安置后的一个潜在并发症.
- IVC直径变化与iIVCT风险之间的关系尚未完全理解.
研究的目的:
- 为了研究最小IVC直径放大百分比与LEDVT患者IVCF安置后iIVCT发生率之间的关联.
- 确定最小IVC直径放大百分比是否是iIVCT的独立风险因素.
主要方法:
- 对113名接受IVCF安置的LEDVT患者进行了回顾性单中心研究.
- 计算机断层扫描用于测量IVC直径在IVCF放置之前和之后.
- 使用多变量考克斯回归和倾向分数匹配 (PSM) 来分析最小IVC直径放大百分比和iIVCT发生率之间的关系.
主要成果:
- 在最小IVC直径放大百分比和iIVCT发病率 (调整HR=1.02,p<.001) 之间,独立于其他因素,发现了显著的正相关性.
- PSM证实了这一显著的关联 (HR = 1.01,p < .001).
- 限制性立方线分析显示出非线性,s形的剂量反应关系,在<37.3%放大时具有值效应,低于此,iIVCT的风险下降.
结论:
- 最低IVC直径放大百分比低于37.3%始终与IVCF放置后iIVCT风险降低有关.
- 最低最小的IVC直径放大百分比在这个患者群体中起到对iIVCT发病率的保护作用.
- 这些发现强调了IVC直径变化在预测IVCF后IVCT风险方面的重要性.
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