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Updated: Jul 1, 2025

Modeling Paracrine Noncanonical Wnt Signaling In Vitro
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一个Wnt10a-Notch信号轴控制赫特维格的上皮根盖细胞行为在根裂模式的过程中

Kai Sun1, Miao Yu1, Jiayu Wang1

  • 1Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, China.

International journal of oral science
|March 14, 2024
PubMed
概括

Wnt10a对于牙根发育至关重要. 失去Wnt10a会扰乱赫特维格上皮根盖 (HERS) 细胞的增殖和分裂,从而导致牛牙. 激活Notch信号部分挽救了这个缺陷.

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