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Updated: Jul 1, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

Published on: June 12, 2021

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全球STING模仿剂通过优选激活瘤控制信号通路来提高抗瘤免疫力

Ying Wang1, Sirui Li2,3, Mengying Hu4

  • 1Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Nature nanotechnology
|March 14, 2024
PubMed
概括

一种通过脂质纳米颗粒传递的全新通用STING模仿剂 (uniSTING) 通过激活抗瘤免疫力有效治疗各种癌症,即使在缺乏STING表达的瘤中也是如此. 这种方法克服了当前STING治疗的局限性.

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