迷你PCNL - 对于患有结石病的慢性病患者来说是一大好处
Faiz Manzar Ansari1, Sajad Ahmad Para1, Mohammad Saleem Wani2
1Department of Urology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, India.
Arab journal of urology
|March 14, 2024
概括
迷你透皮瘤切除术 (PCNL) 在患有慢性病 (CKD) 和结石的患者中显著改善功能. 这种最少的侵入性手术提供了高的石头清除和可比标准PCNL的安全性.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 腎臟病學 (nephrology) 是一種醫學.
- 最少侵入性的手术
背景情况:
- 尿路结石病影响3.2%的末期病患者 (ESRD),可能导致损伤.
- 透皮结石切除术 (PCNL) 是复杂结石的黄金标准,技术的进步导致了更小的仪器.
- 慢性病 (CKD) 复杂化了石头的管理,需要安全有效的治疗选择.
研究的目的:
- 评估迷你PCNL在CKD患者的安全性和可行性.
- 为了评估迷你PCNL对功能的影响,具体估计膜过率 (eGFR).
- 确定迷你PCNL对CKD阶段和术后结果的影响.
主要方法:
- 一项前性研究包括46名患有结石和CKD第3阶段或更高的成年患者.
- 进行了迷你PCNL,并使用基线和6个月随访时的MDRD方程测量了eGFR.
- 二级结局包括并发症率,石头清除和住院时间.
主要成果:
- 迷你PCNL在6个月后显示出eGFR的显著改善 (平均差异为14.25毫升/分钟/1.73米2;p<0.01).
- 实现了89.5%的高无结石率.
- 并发症的发生率与标准PCNL相似.
结论:
- 迷你PCNL是对CKD患者结石的安全有效治疗方法.
- 该程序导致显著的功能改善和高石头清除.
- 迷你PCNL代表了一种有价值的治疗选择,用于在CKD的背景下管理结石病.
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