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Updated: Jul 1, 2025

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
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破坏p38MAPK-MSK1-CREB-MITF-M通路,以防止皮肤的多颜色

Song-Hee Kim1, Jiyeon Lee1, Jihye Jung1

  • 1College of Pharmacy, Chungbuk National University, Cheongju 28160, Korea.

International journal of biological sciences
|March 14, 2024
PubMed
概括

胺-2-butanol (BI2B) 通过阻断MKK3-p38MAPK-MSK1-CREB-MITF-M通路来抑制UV-B诱导的皮肤超色素化. 这种化合物减少了黑色素的产生,为色素系疾病提供了一种策略.

关键词:
MKK3 MKK3 MKK3 MKK3 在线播放黑色素的颜色是黑色素的颜色.紫外线 UV-B 是一种班齐米达-2-布坦醇是一种α-MSHH 的情况.

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