评估草果提取物的抗氧化,抗炎和抗菌活性:一个体外研究
R Gomathi1, T N Umamaheswari1, Roland Prethipa1
1Department of Oral Medicine and Radiology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, IND.
Cureus
|March 14, 2024
概括
拉斯伯里提取物在体外显示出显著的抗微生物,抗氧化和抗炎性质. 这些发现表明其作为一种天然治疗剂的潜力,特别是在口腔医学中.
科学领域:
- 植物化学 植物化学
- 药理学 药理学是指药理学的学科.
- 自然产品 自然产品
背景情况:
- 蓝 (Rubus idaeus) 富含具有营养特性的生物活性化合物.
- 蓝的消费与糖尿病,癌症和心脏病等慢性疾病的风险降低有关.
研究的目的:
- 为了研究水性拉斯伯里提取物的抗菌,抗氧化和抗炎作用.
- 评估拉斯伯里提取物作为天然治疗剂的潜力.
主要方法:
- 水性拉斯伯里提取物是由Rubus idaeus.制备的.
- 使用阿加尔井扩散对Streptococcus mutans和Candida albicans进行了抗菌活性测试.
- 通过DPPH和过氧化激素扫除试验评估的抗氧化活性.
- 使用牛血清白蛋白和卵白蛋白变性试验评估的抗炎活性.
主要成果:
- 树提取物在100μL时对S. mutans (26毫米区) 和C. albicans (24毫米区) 显示出强烈的抗菌活性.
- 提取物表现出显著的抗氧化活性:87.42%的过氧化清除和91.12%的DPPH基因抑制在50μg/mL.
- 观察到有效的抗炎活性,在50μg/mL时抑制了80%的BSA变性和77%的卵蛋白.
结论:
- 水性拉斯伯里提取物具有显著的抗微生物,抗氧化和抗炎性质.
- 提取物显示承诺作为口腔医学中的天然替代品,用于诸如口腔粘膜病变,角膜炎和口腔癌等疾病.
- 建议进行进一步的体内研究和临床试验,以验证治疗潜力.
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