在热量限制和禁食期间对必需微量营养素的要求
Weiguo Zhang1, Peng Chen2, Shaofeng Huo3
1Las Colinas Institutes, Irving, TX, United States.
Frontiers in nutrition
|March 14, 2024
概括
热量限制 (CR) 是一种体重管理策略,可能会影响微量营养素摄入量. 需要进一步的研究来确定在长时间的负能量平衡期间最佳的维生素和矿物质需求.
科学领域:
- 营养科学 营养科学
- 代谢研究 代谢研究
- 衰老研究研究 衰老研究
背景情况:
- 卡路里限制 (CR) 是一种非药物治疗方法,用于控制体重和控制肥胖.
- CR可能会影响疾病的发病和衰老过程,可能促进长寿.
- 保持能量平衡 (输入与支出) 是CR的核心,通常涉及初始负能量平衡.
研究的目的:
- 为了突出CR期间微量营养素摄入量减少的潜力.
- 在CR期间确定人类研究中关于精确的微量营养素需求的差距.
- 强调需要基于证据的探索负能量平衡中微量营养素需求的需要.
主要方法:
- 对CR的历史人类病例报告的审查.
- 对非人类灵长类动物的长寿研究的分析.
- 对最近关于CR和补充剂的随机对照试验 (RCT) 的审查.
- 在人体CR研究中发现研究缺口.
主要成果:
- 历史的CR报告和灵长类动物研究表明,保持足够的微量营养素摄入量 (AI) 或推的饮食补贴 (RDA).
- 最近的RCT支持在CR期间每天补充多种维生素和矿物质.
- 在长期负能量平衡期间对特定微量营养素需求的人类研究中存在一个显著的差距.
结论:
- 目前微量营养素的AI/RDA可能不适合由于CR导致长期负能量平衡的个体.
- 进一步的研究对于了解CR期间维生素和矿物质的吸收,利用和新陈代谢至关重要.
- 需要精确营养方法来确定CR患者的最佳微量营养素摄入量.
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