饮食模式和高尿血的风险:一个更新的系统性审查和观测研究的元分析
Zhao-Yan Wen1, Yi-Fan Wei2, Ye-Huan Sun1,3
1Scientific Research Management Department, Chaohu Hospital Affiliated to Anhui Medical University, Hefei, China.
Frontiers in nutrition
|March 14, 2024
概括
基于植物的饮食与较低的高尿血症 (HUA) 风险有关,而基于动物和甜食的饮食模式增加了HUA风险. 这一系统性审查和元分析澄清了饮食对HUA的影响.
科学领域:
- 营养科学 营养科学
- 流行病学 流行病学
- 代谢健康 代谢健康
背景情况:
- 饮食模式越来越多地被认为对代谢健康的作用.
- 之前关于饮食模式与高尿素血症 (HUA) 风险之间的关联的研究已经产生了不一致的结果.
- 需要更新系统性审查和元分析来澄清这些关系.
研究的目的:
- 量化评估后期饮食模式与患上高尿路血症 (HUA) 的风险之间的关联.
- 提供来自观察研究的证据的最新综合.
- 为了确定与HUA风险相关的特定饮食模式.
主要方法:
- 从Embase,PubMed和Web of Science的英语出版物的系统审查和元分析.
- 包括13项研究,共有163,192名参与者.
- 随机效应模型用于计算总结概率比率 (OR) 和95%置信区间 (CI),并进行子组,灵敏度和元回归分析.
主要成果:
- 基于植物的饮食模式与17%的HUA风险降低有关 (OR = 0.83,95% CI = 0.72-0.94).
- 基于动物的食物模式 (OR = 1.36,95% CI = 1.25-1.47) 和甜食模式 (OR = 1.24,95% CI = 1.06-1.46) 与HUA的风险增加有关.
- 在子组分析中没有发现出版偏差或显著异质性的证据.
结论:
- 基于植物的饮食模式与高尿素血症风险有相反的相关性.
- 基于动物和甜食的饮食模式与高尿素血的风险增加有积极的相关性.
- 饮食选择在调节高尿路血症风险方面发挥着重要作用.
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