的先天性免疫训练,以改善对病原体的防御:一篇评论
Yukinori Yoshimura1,2, Takahiro Nii1, Naoki Isobe1
1Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima 739-8528, Japan.
The journal of poultry science
|March 14, 2024
概括
本综述探讨了疫苗接种和料添加剂,如β-葡萄糖,如何通过训练免疫来增强家禽的先天免疫力. 这可以改善家禽健康和产品安全.
科学领域:
- 兽医免疫学 兽医免疫学
- 禽畜科学 禽畜科学 禽畜科学
- 具有天生的免疫力.
背景情况:
- 鸟类免疫系统对于家禽生产至关重要,确保产品的质量和安全.
- 从历史上看,疫苗接种主要集中在适应性免疫力上,但先天性免疫力增强正在引起人们的注意.
- 训练免疫力是一种与生俱来的免疫记忆形式,涉及表观遗传和代谢变化,在各种动物中观察到.
研究的目的:
- 审查疫苗接种和β-葡萄糖对家禽先天免疫力的潜在影响.
- 探索家禽训练免疫的概念.
- 考虑将这些发现纳入家禽防御的先进策略.
主要方法:
- 关于鸟类天生的免疫力研究的文献综述.
- 对家禽疫苗接种和料添加剂 (特别是β-葡萄糖) 的研究进行分析.
- 检查哺乳动物训练免疫文献以获得比较的见解.
主要成果:
- 有限但越来越多的证据表明,疫苗接种和料添加剂会影响家禽的先天免疫力.
- 表观遗传和代谢重编程是训练免疫力的关键机制.
- β-葡萄糖是一种潜在的饮食成分,可以调节先天免疫力.
结论:
- 疫苗接种和β-葡萄糖显示有希望通过训练免疫来增强家禽的先天免疫力.
- 需要进一步的研究,以充分理解和应用培训免疫概念在家禽中.
- 这些策略可以改善家禽的健康,防御和产品安全.
相关概念视频
01:21Introduction to Innate and Adaptive Immunity
4.0K
The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
4.0K
01:31Defense Against Bacterial Pathogens
1.4K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
1.4K
01:26Defense Mechanism Against Infection
6.5K
Natural flora, body system defenses, and inflammation are natural barriers of the body against infectious agents regardless of previous exposure. Normal floras of the human body refer to the microbial population that colonizes the skin and mucous membranes.
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
6.5K
01:51Vaccinations
44.5K
Overview
44.5K
01:36Humoral Immune Responses
72.7K
Overview
72.7K
01:20Special Features of Adaptive Immunity
812
The adaptive immune system, a crucial component of the overall immune response, offers a highly specialized defense against pathogens. It involves specific cell types and features, enabling it to combat infections effectively and efficiently.
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
The primary cell types involved in adaptive immunity are T cells and B cells. Each type has a unique role in defending the body against pathogens. T cells are responsible for cell-mediated immunity. They identify and eliminate infected cells directly,...
812