在患有抑郁症的患者中,心率变化和C-反应蛋白之间的关联
Soni Singh1, Shraddha Singh1, Neeraja Shukla1
1Department of Physiology, King George Medical University, Lucknow, Uttar Pradesh, India.
Journal of family medicine and primary care
|March 14, 2024
概括
抑郁症与心血管问题有关. 这项研究发现,某些心率变化 (HRV) 测量,表明自主神经系统功能,与抑郁患者的C-反应蛋白 (CRP) 水平相关.
科学领域:
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
- 身体生理学 身体生理学
背景情况:
- 抑郁症与心血管 (CV) 发病率和死亡率的增加有关.
- 炎症和自主神经系统 (ANS) 功能障碍被认为是潜在的促成因素.
- 现有的研究突出显示了炎症途径和ANS之间的联系.
研究的目的:
- 调查心率变化 (HRV) 参数与C反应蛋白 (CRP) 水平之间的关系.
- 在没有其他并发疾病的抑郁患者中探索这些关系.
主要方法:
- 一项涉及65名通过ICD-10标准诊断的非药物治疗抑郁症患者的横截面研究.
- 短期HRV使用心电图 (ECG) 记录了5分钟.
- 使用ELISA测试来量化C反应蛋白 (CRP) 水平.
主要成果:
- 心率变化 (HRV) 测量与脉率,血压或BMI没有相关性.
- 在C反应蛋白 (CRP) 和非常低频率 (VLF),低频率 (LF) 以及HRV的LF/HF比率之间观察到正相关性.
- 在CRP和HRV的高频率 (HF) 之间发现了负相关性.
结论:
- 休息HRV和CRP测量可以帮助识别抑郁症患者的心血管疾病风险.
- 低HRV和高CRP要求立即进行医疗评估和对心血管风险进行管理.
更多相关视频
06:55An Unpredictable Chronic Mild Stress Protocol for Instigating Depressive Symptoms, Behavioral Changes and Negative Health Outcomes in Rodents
Published on: December 2, 2015
22.5K
06:24Examining Changes in HRV and Emotion Following Artmaking with Three Different Art Materials
Published on: January 11, 2020
6.1K
相关概念视频
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
81
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
81
Psychoneuroimmunology: Cardiovascular Disease
30
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
30
Factors Influencing Heart Rate
2.6K
The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
2.6K
Introduction to Stress and Lifestyle
107
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
107
