在急性无重量状态下脉静脉流动的动态
Karina Marshall-Goebel1, Stuart M C Lee2, Jason R Lytle2
1NASA Johnson Space Center, Houston, Texas, United States.
Journal of applied physiology (Bethesda, Md. : 1985)
|March 14, 2024
概括
太空飞行会导致液体的移动,导致内静脉 (IJV) 膨胀. 急性无重量进一步增加了IJV大小,并可能导致左侧IJV的流静止,可能增加血栓形成风险.
科学领域:
- 心血管生理学心血管生理学
- 太空医学 太空医学
- 静脉血液动力学 静脉血液动力学
背景情况:
- 太空飞行会诱导脑膜液体的移动,改变静脉血液动力学.
- 在太空任务期间,内静脉 (IJV) 膨胀和潜在的血栓形成风险是令人担忧的.
研究的目的:
- 为了研究急性无重力 (0-G) 对IJV尺寸和血液流动动学的影响.
- 为了评估在抛物线飞行期间IJV截面面积 (CSA) 和流量模式的变化.
主要方法:
- 两维 (2D) 超声波测量了IJV CSA. 两维 (2D) 超声波测量了IJV CSA.
- 多普勒超声波描述了静脉血液流动模式.
- 在抛物线飞行过程中,测量是在坐姿,卧姿 (1G) 和卧姿 (0G) 条件下进行的.
主要成果:
- 仰卧姿势在地球上增加了IJV CSA (1-G).
- 进入0-G进一步增加了双边的IJV CSA,相比躺着的1-G.
- 在0-G期间,在一名参与者的左侧IJV中观察到流静止,在水平飞行期间持续存在.
结论:
- 急性无重量状态会改变左侧IJV的大脑外流动力学.
- 这些变化可能会增加太空飞行期间静脉血栓形成的风险.
- IJV膨胀和潜在的流动静止是宇航员健康的重要发现.
相关概念视频
Venous Return
4.2K
The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
4.2K
Imbalances in Cardiac Output
1.4K
The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send...
1.4K
Weightlessness
5.0K
When an object is dropped, it accelerates toward the center of the Earth. If the net external force on the object is its weight, it is said to be in free fall; that is, the only force acting on the object is gravity. Galileo was instrumental in showing that, in the absence of air resistance, all objects fall with the same acceleration g. However, when objects on the Earth fall downward, they are never truly in free fall, because there is always some upward resistance force from the air acting...
5.0K
Assessment of the Cardiovascular System III: Palpation
326
Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
326
Pressure Relationships in Thoracic Cavity
2.3K
Breathing, otherwise known as pulmonary ventilation, is the process of air movement into and out of the lungs. The main mechanisms propelling pulmonary ventilation are atmospheric pressure (Patm), intra-pulmonary (Ppul ) or intra-alveolar pressure (Palv) within the alveoli, and intrapleural pressure (Pip) within the pleural cavity.
Breathing Mechanisms
Both intra-alveolar and intrapleural pressures rely on specific lung properties. The ability to breathe—allowing air to enter the lungs...
Breathing Mechanisms
Both intra-alveolar and intrapleural pressures rely on specific lung properties. The ability to breathe—allowing air to enter the lungs...
2.3K
Pressure Variation in a Fluid at Rest
253
In a fluid at rest, the pressure at any point beneath the fluid surface depends solely on the depth, not on the container's shape or size. This principle, known as hydrostatic pressure, arises because, in stationary fluids, there is no acceleration, meaning the forces within the fluid balance out. Only vertical forces, caused by the weight of the fluid above, contribute to pressure changes with depth.
When measuring pressure at two different levels within the fluid, the difference in...
When measuring pressure at two different levels within the fluid, the difference in...
253


