透鼻内镜在儿科异性食道炎的内镜和组织学效用
Eliana Shaul1,2, Kanak V Kennedy1, Zachary C Spergel1
1Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Journal of pediatric gastroenterology and nutrition
|March 14, 2024
概括
无透鼻腔内镜 (TNE) 提供了一种节省时间的替代方案,用于儿科异性食道炎 (EoE) 监测. 这种方法为EoE组织学评分提供了与传统内镜可比的诊断准确性.
科学领域:
- 胃肠病学 胃肠病学
- 儿科内镜术 儿科内镜术
- 食道疾病 食道疾病
背景情况:
- 乙性食道炎 (EOE) 通常需要经常进行内镜监测.
- 标准食管胃管腺镜检查 (EGD) 对儿科患者来说可能是繁的.
- 无透鼻腔内镜 (TNE) 提供了一个不那么侵入性的替代方案.
研究的目的:
- 评估TNE活检对EoE组织学评分的充分性.
- 在EOE患者中比较TNE和EGD之间的手术时间和内镜检测结果.
- 评估TNE对长期EoE疾病监测的有用性.
主要方法:
- 一个回顾性比较66名儿科EoE患者接受TNE与132名接受EGD的匹配对照.
- 对手术时间,视觉内镜检查结果和EoEHSS组件的分析.
- 匹配标准包括年龄和疾病活动.
主要成果:
- 经过TNE的患者在胃肠道病房的时间显著减少 (1.94小时少,p < 0.0001).
- 视觉内镜发现在TNE和EGD组之间是可比的.
- 大多数EoE组织学评分系统 (EoEHSS) 的组件都是可比的.
结论:
- 无透鼻内镜是一种可行的和有效的工具,用于儿科EoE监测.
- TNE为EoEHSS评估提供了足够的活检,与标准EGD相比.
- 应考虑TNE用于临床试验和EoE的长期管理.
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