慢性辅助性中耳炎:对微生物学和抗菌素敏感性模式的前性描述性研究
Tessa K Suttle1, Timothy Els1, Julia Toman2
1Otorhinolaryngology Department, Port Elizabeth Provincial Hospital (PEPH), Port Elizabeth, South Africa.
概括
菌感染是慢性性中耳炎 (CSOM) 的常见原因,需要培养导向治疗. 这项研究确定了南非的关键病原体及其对抗生素敏感性.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 慢性性中耳炎 (CSOM) 是一种持续的耳部感染.
- 识别致病原体及其耐药性模式对于有效治疗至关重要.
研究的目的:
- 确定导致CSOM的主要病原体及其对抗菌素敏感性.
- 评估CSOM患者中胆固醇瘤的患病率.
主要方法:
- 在伊丽莎白港省医院进行了一项前性描述性研究.
- 来自169名CSOM患者的耳部拭子被分析为微生物培养和灵敏度.
- 对患者的病历进行了审查,以确定胆固醇瘤的诊断.
主要成果:
- 菌类分离物 (Candida,Aspergillus) 是最常见的 (20.8%),其次是 Pseudomonas aeruginosa (12.4%) 和 Staphylococcus aureus (11.8%).
- 在3.6%的病例中发现了菌根结核病.
- 胆固醇瘤存在于17.8%的患者中. 菌对可纳有94.3%的敏感性;P. aeruginosa对piperacillin-tazobactam和cefepime非常敏感.
结论:
- CSOM是一个重大的公共卫生问题.
- 在没有反应的CSOM病例中,应考虑真菌感染.
- 建议在慢性耳部感染中进行培养导向治疗,原因是各种病原体和不同的易感模式.
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