七天跨阿尔卑斯山步道跑对心脏生物标志物和心肌功能的影响
Katrin Esefeld1,2, Marisa Geisberger1, Sophia Marie-Theres Dinges1,2
1Department of Preventive Sports Medicine and Sports Cardiology, TUM School of Medicine and Health, University Hospital 'Klinikum rechts der Isar', Technical University of Munich, Munich, Germany.
Scandinavian journal of medicine & science in sports
|March 14, 2024
概括
强烈的耐力运动暂时会提高像NT-proBNP这样的心脏生物标志物,与短暂的右心室功能障碍有关,但在运动员中没有显示持久的心脏损伤.
科学领域:
- 运动医学 运动医学
- 心脏病学 心脏病学
- 运动生理学 运动生理学
背景情况:
- 强烈的体力炼可以提高心脏生物标志物,这引发了关于生理适应与心肌损伤之间的问题.
- 对于运动员和临床医生来说,了解长时间高体量运动对心脏健康的影响至关重要.
研究的目的:
- 研究连续七天过度耐力运动对心脏生物标志物,功能和组织损伤的影响.
- 为了区分生理反应和极度运动后的心肌损伤的实际情况.
主要方法:
- 七天的步道跑比赛 (跨阿尔卑斯山跑道,267.4公里),每天取血样检测hs-TnT,NT-proBNP和ST2.
- 每隔一天进行心声扫描,并在比赛前后进行心脏磁共振成像 (CMR).
- 对心脏生物标志物,心室功能 (TAPSE) 和结构完整性的分析.
主要成果:
- 在第一阶段和整个比赛中,NT-proBNP显著增加 (3.6倍).
- Hs-TnT呈现上升趋势,并保持高位,而ST2水平保持不变.
- 增加NT-proBNP与轻度,短暂的右心室功能障碍 (TAPSE) 相相关,但通过心声学或CMR没有观察到左心室功能或结构的显著变化.
- 所有生物标志物在比赛后恢复到生理水平.
结论:
- 长时间,高体积的耐力运动会导致NT-proBNP和临时右心室功能障碍的暂时增加.
- 没有发现显著的左心室功能或结构障碍的证据,这表明生理适应而不是心肌损伤.
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