神经生物学和系统生物学的应激弹性,应激弹性
Raffael Kalisch1,2, Scott J Russo3,4, Marianne B Müller1,5
1Leibniz Institute for Resilience Research (LIR), Mainz, Germany.
Physiological reviews
|March 14, 2024
概括
生物弹性包括在压力下保持心理健康. 关键的大脑功能,如认知控制和奖励处理,以及神经可塑性和肠道健康等因素,对于抗压和预防心理健康障碍至关重要.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 系统生物学 系统生物学
背景情况:
- 应激弹性是保持心理健康的能力,尽管逆境.
- 关于弹性的生物研究正在迅速推进,但面临着方法上的挑战.
- 了解性机制可以为与压力相关的疾病的预防性干预提供信息.
研究的目的:
- 审查和批判性地讨论行为,神经成像,神经生物学和系统生物学研究对成年人应激弹性的发现.
- 识别神经机制,以保护免受与压力相关的功能障碍.
- 探索潜在的生物干预措施,以提高应激弹性.
主要方法:
- 审查现有的文学行为,神经成像,神经生物学和系统生物学研究的压力弹性.
- 在性研究中的方法论挑战的批判性讨论.
- 跨不同生物层面的发现的整合.
主要成果:
- 海马和前额叶皮层的功能 (模式分离,认知控制) 可能会在单一的压力因素后防止病态恐惧.
- 奖励系统的功能 (追求,品尝) 可能会防止由慢性压力因素引起的焦虑-抑郁谱系障碍.
- 在压力下神经系统完整性与神经可塑性,免疫调节和肠道微生物组/屏障完整性之间的新兴联系.
结论:
- 特定的神经系统及其功能与不同形式的应激弹性有关.
- 神经可塑性,免疫调节和肠道健康是干预的潜在生物目标.
- 需要进一步的研究来克服方法上的障碍,并将发现转化为临床应用.
相关概念视频
Stress Prevention and Stress Management Techniques II
39
Personality types, particularly Type A and Type B, significantly influence how individuals respond to stress. These personality distinctions are marked by varying levels of ambition, competitiveness, and coping styles, all of which shape an individual's resilience to stressors.
Type A Personality: Driven and Easily Stressed
Individuals with Type A personalities are often highly competitive and ambitious and operate with a strong sense of urgency. Commonly labeled as...
Type A Personality: Driven and Easily Stressed
Individuals with Type A personalities are often highly competitive and ambitious and operate with a strong sense of urgency. Commonly labeled as...
39
Physiological Foundation of Stress
57
Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
Adrenaline triggers the...
Role of the Sympathetic Nervous System
Adrenaline triggers the...
57
Introduction to Stress and Lifestyle
107
Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
107
Stress Prevention and Stress Management Techniques I
47
Stress prevention and management are crucial for maintaining well-being and building resilience. Techniques to manage stress include cultivating qualities like conscientiousness, a sense of personal control, and self-efficacy. Each of these traits significantly reduces stress and promotes healthier lifestyle choices and outcomes.
Conscientiousness
Conscientious individuals tend to be organized, responsible, and disciplined. They prioritize completing tasks and following structured routines,...
Conscientiousness
Conscientious individuals tend to be organized, responsible, and disciplined. They prioritize completing tasks and following structured routines,...
47
Psychoneuroimmunology: Cardiovascular Disease
30
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
A key area of focus in PNI is the relationship between stress and coronary...
30
Introduction to Biological Bases of Psychology
3.2K
Biopsychology serves as a vital bridge connecting the intricate domains of biology and psychology, shedding light on how biological systems influence psychological phenomena. This field scrutinizes the biological substrates of behavior and mental processes, emphasizing the nervous system along with the roles of neurotransmitters, hormones, and genetics. It also incorporates evolutionary perspectives to explain the adaptive nature of mental functions.
The nervous system, the cornerstone of...
The nervous system, the cornerstone of...
3.2K


