从理论到治疗:对干细胞在与年龄相关的黄斑变性衰退中的进展进行了文献计量和视觉研究
Weina Liu1, Chuanhe Zhang1, Fengqi Jiang1
1Jinan University, Guangzhou, China.
Cytotherapy
|March 14, 2024
概括
这份图书统计分析显示,全球对于与年龄相关的黄斑变性 (AMD) 的干细胞研究显著增加. 美国在出版物方面处于领先地位,研究转向临床应用和安全.
科学领域:
- 再生医学和眼科医学的眼科.
- 干细胞生物学和治疗方法
- 科学文献的图书统计分析.
背景情况:
- 人类多能干细胞 (hPSC),包括胚胎干细胞 (ESC) 和诱导多能干细胞 (iPSC),对退行性疾病具有巨大的治疗前景.
- 与年龄相关的黄斑变性 (AMD) 是视力丧失的重要原因,干细胞治疗代表了潜在的治疗途径.
- 缺乏专门针对AMD的干细胞研究的综合图书统计分析.
研究的目的:
- 进行干细胞和与年龄相关的黄斑变性 (AMD) 研究的文献分析.
- 绘制基础和新兴研究领域,主要贡献者和出版趋势的地图.
- 在这个专业领域确定全球研究成果和合作模式.
主要方法:
- 对2000年至2022年间发表的文章和评论进行文献计量分析.
- 数据来源于科学网络核心集合的数据.
- 使用VOSviewer,CiteSpace,R语言和Microsoft Excel 365进行分析和可视化.
主要成果:
- 总共有539篇出版物被确定,显示出全球对AMD干细胞的兴趣日益增长.
- 美国在出版物和引用影响方面成为主要贡献者.
- 主要研究主题包括"临床试验"",干细胞疗法"",视网膜有机体"和"视网膜原生细胞".
结论:
- 对于AMD的干细胞研究已经经历了实质性的增长,强调了加强国际合作的必要性.
- 研究重点正在从基本的细胞培养和安全发展到临床预后和移植后结果.
- 该领域正在从实验室研究向AMD干细胞治疗的临床应用过渡.
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