测试性与精神病理学之间的关系是否可以通过ABCD中的结构形态学来解释
Leigha Rose1, Benjamin Listyg1, Max M Owens2
1Department of Psychology, University of Georgia.
Journal of psychopathology and clinical science
|March 14, 2024
概括
结构性大脑差异解释了儿童精神病理学中性别差异的小部分,特别是外部化行为. 这些发现突出了大脑形态与青年的行为差异之间的微妙联系.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 精神病学是一个精神病学.
背景情况:
- 心理病理学中确定的性别差异:女性在内化方面更高 (INT),男性在外化方面更高 (EXT).
- 青少年大脑认知发展 (ABCD) 研究提供了关于大脑结构和行为的纵向数据.
研究的目的:
- 调查结构性大脑差异是否调解了性别和精神病理之间的关系.
- 量化大脑形态测量在INT和EXT精神病理学中的性别差异的程度.
主要方法:
- 利用了来自ABCD研究的两个数据波 (N = 6,778每波).
- 检查了性别,结构性大脑形态测量和精神病理学 (INT和EXT) 之间的关系.
- 统计分析以确定大脑变量是否调解性心理病理学关联.
主要成果:
- 在结构性大脑形态测量中观察到强烈的性别差异,在所有波段中都保持一致.
- 很少有大脑形态学变量与INT或EXT精神病理学显著相关,影响规模很小.
- 26个大脑区域部分占性心理病理学关联,主要是外部化行为,影响很小.
结论:
- 在9-12岁的儿童中,结构性大脑变量在统计学上解释了心理病理学中性别差异的很小部分.
- 与内部化相比,调解效应在外部化精神病理方面更为明显.
- 研究结果表明,年轻人与性有关的行为差异存在微妙的神经生物学基础.
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