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在质母细胞瘤中,OGDH和Bcl-xL损失导致合成致死性

Trang Tt Nguyen1, Consuelo Torrini1, Enyuan Shang2

  • 1Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York, USA.

JCI insight
|March 14, 2024
PubMed
概括

质母细胞瘤 (GBM) 的生长通过向TCA循环酶OGDH与CPI-613和BCL-xL与ABT263.3的向来抑制. 这种组合疗法对治疗这种无法治愈的脑癌有前途.

关键词:
亡的途径 亡的途径在瘤学瘤学.

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