输液组替换间隔对重症监护室中中枢线相关的血流感染的影响:INSPIRATION研究的研究协议
Dandan Xu1, Chang Hu1, Jie Xiong2
1Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, 430071, Hubei, China.
Infectious diseases and therapy
|March 14, 2024
概括
这项研究比较了24小时和96小时的输液组替换间隔,以减少重症成人中中枢线相关的血流感染 (CLABSI). 结果将指导在重症监护室 (ICU) 输液组管理的最佳实践.
科学领域:
- 关键护理医学 关键护理医学
- 预防传染病 预防传染病
- 临床试验 临床试验
背景情况:
- 输液组置换间隔在各机构之间有所不同,影响了中线相关血流感染 (CLABSI) 的发生率.
- 有限的高质量证据可指导最佳输液组更换间隔.
- 这项研究解决了对在重症监护中输液组管理的基于证据的建议的需求.
研究的目的:
- 为了比较24小时输液与96小时输液的疗效,在预防CLABSI方面设置替换间隔.
- 评估不同替代策略对中枢静脉接入装置的重症成人中CLABSI率的影响.
主要方法:
- 一个多中心,并行组随机对照试验,涉及1240名成年ICU患者.
- 参与者随机分配到24小时或96小时输液组替换间隔组.
- 主要结局:随机化后28天内CLABSI的发生率.
主要成果:
- 主要结果数据正在等待分析,因为这是一个计划的结果描述.
- 该研究旨在提供关于与不同替代间隔相关的CLABSI率的可靠数据.
结论:
- 这是第一个随机对照试验,直接比较24小时和96小时输液组替换间隔,用于ICU患者的CLABSI预防.
- 结果将为临床实践指南提供信息,用于在重症监护机构的输液组管理.
更多相关视频
10:38Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies
Published on: January 16, 2019
20.2K
09:17Use of a Central Venous Line for Fluids, Drugs and Nutrient Administration in a Mouse Model of Critical Illness
Published on: May 2, 2017
8.9K
相关概念视频
01:22Healthcare Associated Infections II: Preventive Measures
2.6K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.6K
01:27Parentral Nutrition: Centeral and Peripheral Parental Nutrition
153
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
153
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
4.2K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.2K