伪膜性结肠炎和帕拉巴克特罗伊德菌种的细菌病:一种罕见的临床表现
Catherine Hsu1, Claudia Moore-Gillon1, Mathew Vithayathil2,3
1Imperial College Healthcare NHS Trust, London, UK.
Clinical journal of gastroenterology
|March 14, 2024
概括
本案例研究详细介绍了一名患有脏疾病的糖尿病患者,在感染Clostridium difficile后,患有肠道细菌,Parabacteroides distasonis和Enterobacter cloacae的败血症. 这突出了与C. difficile有关的肠道无氧血液感染的罕见案例.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 末期脏病 (ESRD) 患者接受血液透析是免疫受损的.
- 糖尿病病是ESRD的主要原因.
- 患有ESRD的患者患有感染的风险增加,包括Clostridium difficile感染 (CDI).
研究的目的:
- 在患有困难菌体感染的患者中报告第一个Parabacteroides distasonis bacteremia病例.
- 在这种背景下,探索肠道转移导致肠道厌氧生物系统性传播的潜在机制.
- 描述患有糖尿病病,数字和并发性CDI的患者的临床过程和管理.
主要方法:
- 病例报告详细介绍了一个患有末期糖尿病病症的患者.
- 临床表现包括急性-慢性数字,败血症,腹痛和腹.
- 诊断程序包括灵活的半导体镜,血液培养,结肠培养和数字片.
主要成果:
- 灵活的半导体镜检查证实了由Clostridium difficile引起的二次性伪膜性结肠炎.
- 血液培养物确定了Parabacteroides distasonis,一种格兰氏阴性肠道无氧生物.
- 肠杆菌cloacae从结肠培养物和数字拭片中分离出来.
- 患者在接受抗生素治疗后恢复过来.
结论:
- 伪膜性结肠炎可能会增加肠道转位,促进肠道厌氧菌的全身传播.
- 这是与Clostridium difficile感染相关的第一个报告的Parabacteroides distasonis bacteremia病例.
- 成功管理涉及抗生素和随后的血管干预数字.
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