描述在入院时出现中线相关血流感染的患者:一项多中心研究
Opeyemi Oladapo-Shittu1, Sara E Cosgrove1,2, Clare Rock1,2
1Johns Hopkins University School of Medicine, Department of Medicine, Baltimore, Maryland, USA.
概括
在入院时存在的中线相关的血液感染 (CLABSI-POA) 具有显著的死亡风险. 了解医院以外的CLABSI-POA负担对于制定有效的预防策略至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 医疗流行病学 医疗流行病学
背景情况:
- 中枢线路相关的血流感染 (CLABSI) 是医院以外的中枢静脉导管 (CVC) 患者的担忧.
- 在非急性护理环境中缺乏针对CLABSI的系统措施.
- 这项研究旨在描述住院时存在的CLABSI (POA),以了解其负担.
研究的目的:
- 为了描述入院患者中CLABSI-POA的负担.
- 确定与CLABSI-POA患者死亡相关的风险因素.
- 在社区环境中为CLABSI的预防策略提供信息.
主要方法:
- 在3个卫生系统中对461名患有CLABSI-POA的患者进行了回顾性横截面分析.
- 根据急性护理指南改编的CLABSI-POA定义.
- 考克斯比例危险分析以确定与30天所有原因死亡率相关的因素.
主要成果:
- 肠杆菌是最常见的病原体 (29.2%).
- 复发的CLABSI发生在25%的患者中,入院期间死亡率为11%.
- 死亡风险随着年龄和缺乏保险而增加,并且随着心血管切除而减少.
结论:
- CLABSI-POA与大量的住院死亡率有关.
- 需要社区监督,以指导急性护理之外的CLABSI预防工作.
- 有针对性的干预措施是必要的,以减少社区中CLABSI的负担.
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