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Updated: Jul 1, 2025

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皮表皮生长因子受体 (EGFR) 是瘤抑制剂E3结合酶FBXW7的标

Matteo Boretto1, Maarten H Geurts1, Shashank Gandhi1,2

  • 1Organoid group, Oncode Institute, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center, 3584 CT Utrecht, the Netherlands.

Proceedings of the National Academy of Sciences of the United States of America
|March 14, 2024
PubMed
概括

结肠器官中的FBXW7突变通过稳定EGFR来降低癌细胞生长对EGF的依赖. 这影响了对EGFR-MAPK抑制剂的敏感性,为结直肠癌治疗提供了洞察力.

关键词:
欧洲农业基金会 (EGFR) 是一个基金.FBXW7FBXW7FFBXW7FF FBXW7FFF FBXW7FF结肠直肠癌是什么意思有机生物有机物

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