Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Preparedness and Phobias01:09

Preparedness and Phobias

100
Human fear responses to certain stimuli, such as darkness, heights, deep water, and blood, can often arise despite the absence of direct negative experiences. This phenomenon is rooted in evolutionary psychology, which posits that humans have developed a predisposition to fear stimuli that historically posed significant survival threats. This predisposition, known as preparedness, suggests that early humans who developed a fear of potentially dangerous entities, such as venomous snakes and...
100
Generalized Anxiety Disorder01:30

Generalized Anxiety Disorder

133
Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
133
Panic Disorder01:27

Panic Disorder

111
Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
111
Role of Amygdala in Memory01:16

Role of Amygdala in Memory

214
The amygdala is a small, almond-shaped structure responsible for processing and storing memories, particularly those linked to emotions like fear and stress. It plays an essential role in the brain's response to emotionally significant events and often enhances memory formation by triggering stress hormone release. The amygdala is vital for encoding and retrieving memories associated with fear or stress, a process that is adaptive by helping organisms avoid dangerous situations.
One of the...
214
Sympathetic Activation01:17

Sympathetic Activation

5.3K
The sympathetic division can influence tissues and organs by releasing norepinephrine at peripheral synapses and distributing epinephrine and norepinephrine through the bloodstream. In times of crisis or stress, sympathetic activation occurs, which is regulated by sympathetic centers in the hypothalamus. As a result, sympathetic activation prepares the body for physical exertion, rapid ATP production, and heightened alertness, allowing individuals to respond effectively to challenging or...
5.3K
The Sympathetic Nervous System01:25

The Sympathetic Nervous System

95.0K
Overview
95.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

The Converging Effects of Different Categories of Antidepressants on the Brain: A Systematic Meta-Analysis of Public Transcriptional Profiling Data From the Hippocampus and Cortex.

Journal of neurochemistry·2026
Same author

Hybrid solid-liquid optics enable scalable, high-resolution light-sheet microscopy across diverse immersion media.

Nature biotechnology·2026
Same author

The Converging Effects of Different Categories of Antidepressants on the Brain: A Systematic Meta-Analysis of Public Transcriptional Profiling Data from the Hippocampus and Cortex.

bioRxiv : the preprint server for biology·2026
Same author

Prucalopride, a serotonin type 4 receptor agonist, induces fast anxiolytic/antidepressant effects and concomitant changes in the gut microbiota.

NPJ biofilms and microbiomes·2026
Same author

Effects of electroconvulsive shock on the function, circuitry, and transcriptome of dentate gyrus granule neurons.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2026
Same author

Psilocybin induces sex- and context-specific recruitment of the stress axis.

Current biology : CB·2025
Same journal

Erratum for the Research Article "Detecting supramolecular organic nanoparticles during heat wave".

Science (New York, N.Y.)·2026
Same journal

Local signals, systemic decline.

Science (New York, N.Y.)·2026
Same journal

The mechanics of liver regeneration.

Science (New York, N.Y.)·2026
Same journal

Computing in a memory with physics.

Science (New York, N.Y.)·2026
Same journal

Retraction.

Science (New York, N.Y.)·2026
Same journal

Making time.

Science (New York, N.Y.)·2026
查看所有相关文章

相关实验视频

Updated: Jul 1, 2025

Author Spotlight: Exploring Neural Correlates of Defensive Behaviors in Fear Learning and Extinction
04:03

Author Spotlight: Exploring Neural Correlates of Defensive Behaviors in Fear Learning and Extinction

Published on: December 15, 2023

895

转换到普遍的恐惧

Rene Hen1,2, Samuel Schacher1,2

  • 1Departments of Psychiatry and Neuroscience, Columbia University, New York, NY, USA.

Science (New York, N.Y.)
|March 14, 2024
PubMed
概括
此摘要是机器生成的。

压力会改变大脑的化学反应, 这种神经递质开关解释了为什么无害的情况会引发焦虑.

更多相关视频

A Novel Pavlovian Fear Conditioning Paradigm to Study Freezing and Flight Behavior
09:26

A Novel Pavlovian Fear Conditioning Paradigm to Study Freezing and Flight Behavior

Published on: January 5, 2021

6.7K
Fear Incubation Using an Extended Fear-Conditioning Protocol for Rats
13:38

Fear Incubation Using an Extended Fear-Conditioning Protocol for Rats

Published on: August 22, 2020

8.2K

相关实验视频

Last Updated: Jul 1, 2025

Author Spotlight: Exploring Neural Correlates of Defensive Behaviors in Fear Learning and Extinction
04:03

Author Spotlight: Exploring Neural Correlates of Defensive Behaviors in Fear Learning and Extinction

Published on: December 15, 2023

895
A Novel Pavlovian Fear Conditioning Paradigm to Study Freezing and Flight Behavior
09:26

A Novel Pavlovian Fear Conditioning Paradigm to Study Freezing and Flight Behavior

Published on: January 5, 2021

6.7K
Fear Incubation Using an Extended Fear-Conditioning Protocol for Rats
13:38

Fear Incubation Using an Extended Fear-Conditioning Protocol for Rats

Published on: August 22, 2020

8.2K

科学领域:

  • 神经科学
  • 心理学
  • 行为科学

背景情况:

  • 压力是人类常见的体验,
  • 大脑对压力的反应涉及复杂的神经化学变化.
  • 了解这些变化对于开发有效的焦虑治疗至关重要.

研究的目的:

  • 调查压力引起的恐惧背后的神经生物学机制.
  • 确定参与这种现象的特定神经递质系统.

主要方法:

  • 使用动物模型研究压力反应.
  • 在特定的大脑区域测量神经递质水平.
  • 观察到对刺激的行为变化.

主要成果:

  • 在压力下观察到神经递质活动的显著变化.
  • 这种神经递质的转换与恐惧反应的发生直接相关.
  • 由于这些神经化学变化,

结论:

  • 压力从根本上改变大脑功能,导致不适当的恐惧.
  • 针对特定的神经递质通路可以减轻压力引起的焦虑.
  • 这项研究为治疗焦虑症提供了新的治疗策略.