阿尔法警报:通过皮肤使用克隆丁用于耐火激发
Samantha Grable, Gary Houchard1, Zach Rossfeld2,1
1MD, MA are with the Division of Palliative Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Journal of pain & palliative care pharmacotherapy
|March 14, 2024
概括
阿尔法-2 激动剂,如透皮克罗尼丁,可以有效地管理息治疗中的焦虑和疼痛. 这一案例凸显了它们的好处,特别是当口服药物是不可行的时.
科学领域:
- 抚慰性护理是一种缓解性护理.
- 老年神经学 老年神经学
- 药理学 药理学 是一个学科.
背景情况:
- 阿尔法-2 激动剂在症状管理中的广泛类效应往往未得到充分的认可.
- 专门的息治疗可以从降低同情输出,诱导镇静和调节疼痛的药物中获益.
- 通过皮肤递送药物为患有动或对口服途径不耐受的患者提供了优势.
研究的目的:
- 突出阿尔法-2激动剂在息护理中的潜力.
- 提出一个案例,证明通过皮肤治疗的克洛尼丁在痴呆症激发的疗效.
- 鼓励对α-2激动剂作为缓解症状的一类进行常规考虑.
主要方法:
- 一个病例报告详细介绍了通过皮肤使用克洛尼丁的使用情况.
- 专注于管理混合痴呆症患者的激动行为.
- 在临床息护理环境中对症状改善的评估.
主要成果:
- 通过皮肤的克洛尼丁有效地改善了兴奋的行为.
- 这项干预措施为患者的出院计划提供了便利.
- 证明了通过皮肤递送α-2激动剂的实用性.
结论:
- 阿尔法-2 激动剂代表了一种有价值的,但未被认可的,用于息护理的药物类别.
- 通过皮肤注射的克洛尼丁可以作为一种有益的选择来控制激动,特别是在无法服用口服药物的患者中.
- 息护理临床医生应该考虑α-2激动剂作为综合性症状管理的一类.
相关概念视频
Sedatives and Hypnotics Drugs: Miscellaneous Agents
171
Sedatives and hypnotics encompass a wide range of substances, each with its unique mechanism of action, uses, and potential adverse effects.
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
Melatonin congeners like ramelteon (Rozerem) and tasimelteon (Hetlioz) selectively bind to melatonin receptors (MT1 and MT2) and thus mimic the actions of melatonin, a hormone that regulates sleep-wake cycles. Tasimelteon is primarily used for non-24-hour sleep-wake disorder, common in blind patients. They are also used to treat conditions like insomnia...
171
Adrenergic Agonists: Therapeutic Uses
772
Adrenergic agonists have diverse therapeutic uses across various medical conditions and emergencies.
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and...
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and...
772
Drug Therapy
43
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
43
Parkinson's Disease: Treatment
264
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
264
Direct-Acting Cholinergic Agonists: Therapeutic Uses
735
Direct-acting cholinergic agonists have many therapeutic uses in various medical fields. Choline esters, including acetylcholine, have limited clinical utility due to their non-selectivity and short duration of action. Still, acetylcholine and carbachol are applied topically during ophthalmologic surgery to induce miosis. Pilocarpine, a muscarinic and ganglionic stimulator, effectively treats open-angle glaucoma and alleviates xerostomia and dry mouth caused by radiotherapy or Sjögren...
735
Psychosis: Goals of Pharmacotherapy
127
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
127


